Extra-cellular matrix changes in Schistosoma mansoni-infected Biomphalaria glabrata
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چکیده
منابع مشابه
Extra-cellular matrix changes in Schistosoma mansoni-infected Biomphalaria glabrata.
Reactivity of snails against parasites exhibits a primitive focal reaction, with encapsulation, phagocytosis and destruction of parasite larvae by macrophage-like cells - the hemocytes. This reaction mimics granulomatous inflammation seen in higher animals. However, different from the latter, little is known about the participation of extra-cellular matrix in such snail defense reactions. Norma...
متن کامل[Influence of hydrocortisone on Schistosoma mansoni development in Biomphalaria glabrata].
The effect of hydrocortisone on the development of BH strain of S. mansoni in B. glabrata snails is evaluated. Snails in a randomly chosen group were submitted to hydrocortisone during four days. In the second day of hydrocortisone exposure, the snails were exposed, each, to ten S. mansoni miracidia. Another group, not treated with hydrocortisone, was exposed to miracidia and observed in the sa...
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Schistosomiasis is an infectious disease infecting mammals as the definitive host and fresh water snails as the intermediate host. Understanding the molecular and biochemical relationship between the causative schistosome parasite and its hosts will be key to understanding and ultimately treating and/or eradicating the disease. There is increasing evidence that pathogens that have co-evolved wi...
متن کاملSchistosoma mansoni: a method for inducing resistance to praziquantel using infected Biomphalaria glabrata snails.
To elucidate the mechanisms of antischistosoma resistance, drug-resistant Schistosoma mansoni laboratory isolates are essential. We developed a new method for inducing resistance to praziquantel (PZQ) using successive drug treatments of Biomphalaria glabrata snails infected with S. mansoni. Infected B. glabrata were treated three times with 100 mg/kg PZQ for five consecutive days with a one-wee...
متن کاملSequential histological changes in Biomphalaria glabrata during the course of Schistosoma mansoni infection.
Biomphalaria glabrata, highly susceptible to Schistosoma mansoni, were seen to shed less and less cercariae along the time of infection. Histological examination kept a close correlation with this changing pattern of cercarial shedding, turning an initial picture of no-reaction (tolerance) gradually into one of hemocyte proliferation with formation of focal encapsulating lesions around disinteg...
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ژورنال
عنوان ژورنال: Memórias do Instituto Oswaldo Cruz
سال: 2003
ISSN: 0074-0276
DOI: 10.1590/s0074-02762003000100017